The MIT Jameel Clinic, in collaboration with the Ragon Institute, has published research in Nature Machine Intelligence introducing MUNIS, an AI tool that can accelerate the development of T cell vaccine candidates.
In tests using experimental data from influenza, HIV and Epstein-Barr virus, MUNIS significantly outperformed existing epitope prediction models, laying the foundation for applications in cancer T cell immunotherapy and autoimmunity research.
Regina Barzilay (MIT Jameel Clinic) commented on the breakthrough: “Through this collaboration with Dr Gaiha and his team, we learned a lot about this fascinating field and are excited about the immense possibilities in using AI algorithms to model the intricacies of the immune system."